The HLA-DR/DQ Genetic Test screens for specific gene patterns (haplotypes) that may increase your susceptibility to mold-related illness and Chronic Inflammatory Response Syndrome (CIRS). This is a non-blood cheek swab test and is particularly useful for individuals who live outside of the U.S. or cannot access LabCorp or Quest facilities.
This test only provides your genetic predisposition and does not diagnose CIRS or assess inflammatory markers. It’s a helpful starting point if you suspect mold exposure.
Why it matters
Approximately 25% of the population carries haplotypes that make them more vulnerable to mold, Lyme, and other environmental biotoxins. Identifying your HLA-DR/DQ pattern can help determine if your immune system may be “genetically blind” to certain toxins, leading to chronic inflammation and illness, even after the exposure ends.
Understanding your genetic profile can help guide further testing, validate your experience, and provide clarity around why you may not be healing on diet alone. It’s also a useful tool for providers building out a CIRS or mold recovery plan.
What this includes
- HLA-DR/DQ Intermediate Resolution Test
- Identification of your unique haplotype(s)
- Determination of whether your genetics fall under mold-sensitive, Lyme-sensitive, multi-susceptible, or low-risk categories
- Written report from Empower Functional Health that includes:
- Explanation of your haplotype and what it means for your health
- Dietary and supplement recommendations
- Suggested next steps for testing or treatment
- Option to join EFH’s CIRS Group Support (additional fee)
- Access to EFH CIRS-specific resources and education tools
How it works
- After purchase, you’ll receive instructions for completing your cheek swab collection.
- The test can be performed internationally and mailed to the processing lab.
- Once results are in, EFH will review your genetics and send a written interpretation via email.
- You’ll receive your personalized report with root-cause insights and practical next steps.
Important notes
- This test only assesses genetic susceptibility and does not include inflammatory or blood-based CIRS markers.
- Testing is performed via cheek swab, not blood.
