Bio-3B-G is a B-Vitamin containing the phosphorylated forms of thiamin (B1), riboflavin (B2) and vitamin B6, with a higher amount of thiamin, as compared to riboflavin and niacin, for increased thiamine needs.
Vitamin B6 is required by enzymes called transaminases in the first step of the breakdown of most amino acids for energy production. Sometimes consuming a meat-based diet can require more B6.
Due to the fact that Bio-3B-G supplies three times the amount of thiamine (“B factor”) in the form of thiamine pyrophosphate and 100% RDA of the B vitamin group, including B2, B3, B6 and B12, it is a beneficial adjunct to a nutrient-dense diet, especially when the body is stressed.
Vitamin B12 and folic acid are responsible for utilization of glycine and serine as methyl donors and for the conversion of the by-product homocysteine to either methionine or to cysteine.
One way to check if this is properly functioning, is by taking the Organic Acids Test.
Key Benefits:
- ENHANCED ENERGY: The human body needs a complex of B vitamins for the metabolism of carbohydrates, fats and proteins, which is how the body converts food into energy. The nutrients found in Bio-3B- G play essential roles in the proper maintenance of metabolic function.
- SUPPORTS HEALTHY RESPONSE TO STRESS: The vitamin B group is not stored in the body like other vitamins and is released from the body within hours after consuming. This can be challenging during times of high stress as we do not always eat properly during these times. Vitamin B6 helps with making neurotransmitters, such as serotonin, which aids in the body’s ability to cope with stress.
- ADRENAL HEALTH: The adrenal glands help regulate a number of processes in the body that affect energy and mood. Bio-3B- G helps support the adrenal glands. It also promotes a sense of calm, and may assist in regulating energy levels and mood.
Bio-3B-G provides biochemically activate forms of the B vitamins, including riboflavin 5- phosphate and cocarboxylase, in lieu of riboflavin and thiamin, respectively. Consequently, fewer enzymatic steps are needed to achieve a fully functional coenzyme. As an example, the first step in the synthesis of NAD is the biochemical conversion of niacin to niacinamide, which then forms nicotinamide mononucleotide, an intermediate for NAD formation.
Riboflavin 5-phosphate is the redox co-enzyme FMN, converted in a single step by flavokinase to FAD, which is more frequently used than FMN.
Flavokinase is regulated by thyroxin, and in adults hypothyroidism may be associated with riboflavin deficiency. In addition, Bio-3B-G provides two complete coenzymes, pyridoxal-5-phosphate and thiamine pyrophosphate (also known as cocarboxylase).
Activation of vitamin B6 involves the phosphorylation of pyridoxine (B6) to pyridoxine phosphate, and its subsequent oxidation to the coenzyme pyridoxal 5-phosphate. Bound to albumin, pyridoxal 5-phosphate characterizes a major storage site and transporter for B6. In the serum of healthy persons, Pyridoxal 5-phosphate comprises between 25% and 60% of the circulating levels of vitamin B6.
The liver is the primary site of pyridoxal 5-phosphate formation. Thus, it is not surprising that up to 90% of people with cirrhotic liver are deficient in vitamin B6. Due to the fact that Bio-3B-G supplies three times the amount of thiamine (“B factor”) in the form of thiamine pyrophosphate and 100% RDA of the B vitamin group, including B2, B3, B6 and B12, it may be a beneficial adjunct in nutritionally supporting normal homoeostatic mechanisms, particularly during stress and/or with elevated blood pressure.
